Racial disparities affect the association between gestational urinary phthalate mixtures and infant genital measures.

ABSTRACT:

Background

Phthalates are ubiquitous anti-androgenic endocrine disrupting chemicals found in personal care products, medications, and many plastics. Studies have shown a racial disparity in phthalates exposure among U.S. women, which may also impact fetal development.

Methods

We conducted a prospective cohort study of gestational exposure to a phthalates mixture in a racially-diverse population to determine their association with genital development. Mid-gestation (18-22 weeks) urine was collected from 152 women who self-identified as non-Hispanic Black and 158 women who self-identified as non-Hispanic White in Charleston, South Carolina between 2011 and 2014. We measured eight phthalate monoester metabolites in urine using liquid chromatography tandem-mass spectrometry. Mid

SUBMITTER: Varde M 

PROVIDER: S-EPMC10749323 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature