Additional Sarasinosides from the Marine Sponge Melophlus sarasinorum Collected from the Bismarck Sea.

ABSTRACT: In our continuing efforts to describe the biological and chemical diversity of sponges from Kimbe Bay, Papua New Guinea, the known 30-norlanostane saponin sarasinoside C₁ (1) was identified along with six new analogues named sarasinosides C₄, C₅, C₆, C₇, C₈, and C₉ (2-7) from the sponge Melophlus sarasinorum. The structures of the new compounds were elucidated by analysis of 1D and 2D NMR and HRMS data, as well as comparison with literature data. All new compounds are characterized by the same tetraose moiety, β-d-Xylp-(1→6)-β-d-GlcNAcp-(1→2)-[β-d-GalNAcp-(1→4)]-β-d-Xylp, as described previously for sarasinoside C₁, but differed in their aglycone m

SUBMITTER: O'Brien S 

PROVIDER: S-EPMC10749473 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature