Effects of early postnatal gastric and colonic microbiota transplantation on piglet gut health.

ABSTRACT:

Background

Diarrhea is a major cause of reduced growth and mortality in piglets during the suckling and weaning periods and poses a major threat to the global pig industry. Diarrhea and gut dysbiosis may in part be prevented via improved early postnatal microbial colonization of the gut. To secure better postnatal gut colonization, we hypothesized that transplantation of colonic or gastric content from healthy donors to newborn recipients would prevent diarrhea in the recipients in the post-weaning period. Our objective was to examine the impact of transplanting colonic or gastric content on health and growth parameters and paraclinical parameters in recipient single-housed piglets exposed to a weaning transition and challenged with enterotoxigenic Escherichia coli (ETEC).

Metho

SUBMITTER: Larsen C 

PROVIDER: S-EPMC10749501 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature