Three cases of suspected pleuroparenchymal fibroelastosis after allogeneic hematopoietic cell transplantation.

ABSTRACT: This article reports the clinical course and imaging findings of three cases of suspected pleuroparenchymal fibroelastosis (PPFE) after allogeneic hematopoietic cell transplantation (HCT). All patients complained of dyspnea more than 5 years after HCT, had progressive restrictive deficits on respiratory function tests, and presented with pneumothorax, pleural thickening, or exacerbation of consolidation in the upper lobe of the lung. Though lung biopsy was not done in all three cases, the clinical findings and results of spirometry were compatible with those of PPFE. PPFE has been sporadically reported as a pulmonary complication of allogeneic HCT; however, clinical diagnostic criteria other than histological diagnosis and treatment methods have not yet been established. The accumulation o

SUBMITTER: Morikawa S 

PROVIDER: S-EPMC10749731 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature