Prenatal vitamin B12 status and cognitive functioning in children at 4 years of age: The ECLIPSES Study.

ABSTRACT: Maternal vitamin B12 deficiency has been associated with disturbed cognitive functioning in offspring at different ages during childhood. However, this association has not been explored in pre-school-age children. The objective of this study was to examine the association between maternal vitamin B12 levels at the beginning and end of pregnancy and cognitive functioning in their children at 4 years of age. This longitudinal prospective study included a subsample of pregnant women and their children aged 4 years (n = 249) who participated in the ECLIPSES Study conducted in the province of Tarragona, Spain, from 2013 to 2017. Maternal vitamin B12 concentrations were determined in the first and third trimesters, and sociodemographic, nutritional and psychological data were collected. The chil

SUBMITTER: Cruz-Rodriguez J 

PROVIDER: S-EPMC10750008 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature