Utility of four machine learning approaches for identifying ulcerative colitis and Crohn's disease.

ABSTRACT:

Objective

Peripheral blood routine parameters (PBRPs) are simple and easily acquired markers to identify ulcerative colitis (UC) and Crohn's disease (CD) and reveal the severity, whereas the diagnostic performance of individual PBRP is limited. We, therefore used four machine learning (ML) models to evaluate the diagnostic and predictive values of PBRPs for UC and CD.

Methods

A retrospective study was conducted by collecting the PBRPs of 414 inflammatory bowel disease (IBD) patients, 423 healthy controls (HCs), and 344 non-IBD intestinal diseases (non-IBD) patients. We used approximately 70 % of the PBRPs data from both patients and HCs for training, 30 % for testing, and another group for external verification. The area under the receiver operating characteristic curve (AUC

SUBMITTER: Pei J 

PROVIDER: S-EPMC10750181 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature