Treatments for Trauma-Induced Coagulopathy: Protocol for a Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Trauma-induced coagulopathy (TIC) is a common and potentially life-threatening coagulopathy as a result of traumatic injury, characterized by abnormal blood clotting and bleeding. Although several treatments have been proposed for TIC, their effectiveness and safety remain unclear. Further, numerous systematic reviews and meta-analyses on trauma have been conducted; however, to our knowledge, there is no systematic review and meta-analysis that specifically focuses on TIC management. Therefore, a comprehensive synthesis of the available evidence on interventions for TIC is needed.

Objective

This systematic review and meta-analysis aim to evaluate the effectiveness and safety of interventions for the management of TIC.

Methods

We will conduct a systematic re

SUBMITTER: Itagaki Y 

PROVIDER: S-EPMC10750238 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature