A cell-based model for size control in the multiple fission alga Chlamydomonas reinhardtii.

ABSTRACT: Understanding how population-size homeostasis emerges from stochastic individual cell behaviors remains a challenge in biology.^{1,2,3,4,5,6,7} The unicellular green alga Chlamydomonas reinhardtii (Chlamydomonas) proliferates using a multiple fission cell cycle, where a prolonged G1 phase is followed by n rounds of alternating division cycles (S/M) to produce 2ⁿ daughters. A "Commitment" sizer in mid-G1 phase ensures sufficient cell growth before completing the cell cycle. A mitotic sizer couples mother-cell size to division number (n) such that daughter size distributions are uniform regardless of mother size distributions. Although daughte

SUBMITTER: Liu D 

PROVIDER: S-EPMC10750806 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature