Distribution of bla_CTX-M-gene variants in E. coli from different origins in Ecuador.

ABSTRACT: The increasing abundance of extended spectrum (β-lactamase (ESBL) genes in E. coli, and other commensal and pathogenic bacteria, endangers the utility of third or more recent generation cephalosporins, which are major tools for fighting deadly infections. The role of domestic animals in the transmission of ESBL carrying bacteria has been recognized, especially in low- and middle-income countries, however the horizontal gene transfer of these genes is difficult to assess. Here we investigate bla_CTX-M gene diversity (and flanking nucleotide sequences) in E. coli from chicken and humans, in an Ecuadorian rural community and from chickens in another location in Ecuador. The bla_CTX-M associated sequences in isolates from humans and chickens in t

SUBMITTER: Valenzuela X 

PROVIDER: S-EPMC10751039 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature