Association between thyroid hormone levels in the acute stage of stroke and risk of poststroke depression: A meta-analysis.

ABSTRACT:

Background

Thyroid hormones have been indicated to be associated with depression, but their relationship with poststroke depression (PSD) remains controversial. Therefore, we performed a meta-analysis to explore the correlation between thyroid hormone levels in acute stroke and PSD.

Methods

We searched databases for eligible studies. Standard mean differences (SMD) and 95% confidence intervals (CI) were applied to evaluate the association among levels of thyroid hormones, including thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), and free thyroxine (FT4), in acute stroke patients and the risk of PSD.

Results

A total of 13 studies were included in the analysis. Compared to non-PSD patients, PSD patients had remarkably lower serum TSH and FT3 levels (TSH:

SUBMITTER: Fu J 

PROVIDER: S-EPMC10751399 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature