Increased adipose tissue is associated with improved overall survival, independent of skeletal muscle mass in non-small cell lung cancer.

ABSTRACT:

Background

The prognostic significance of non-cancer-related prognostic factors, such as body composition, has gained extensive attention in oncological research. Compared with sarcopenia, the prognostic significance of adipose tissue for overall survival in non-small cell lung cancer remains unclear. We investigated the prognostic value of skeletal muscle and adipose tissue in patients with non-small cell lung cancer.

Methods

This retrospective study included 4434 patients diagnosed with non-small cell lung cancer between January 2014 and December 2016. Cross-sectional areas of skeletal muscle and subcutaneous fat were measured, and the pericardial fat volume was automatically calculated. The skeletal muscle index and subcutaneous fat index were calculated as skeletal muscl

SUBMITTER: Tao J 

PROVIDER: S-EPMC10751412 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature