Impact of sarcopenia on the survival of patients undergoing liver transplantation for decompensated liver cirrhosis.

ABSTRACT:

Background

Patients with decompensated cirrhosis (DC) are prone to skeletal muscle loss, namely, sarcopenia, before liver transplantation (LT). While sarcopenia is reportedly associated with adverse outcomes after LT, these findings are limited owing to mixed diseases and retrospective data. We investigated the association between sarcopenia and 1-year overall survival (OS) in patients with DC after LT and established and validated a prediction model for postoperative OS based on sarcopenia.

Methods

Overall, 222 consecutive patients who underwent LT at our centre were registered between September 2020 and June 2022. Third lumbar spine skeletal muscle mass index was measured using computed tomography. Patients were divided into sarcopenia and non-sarcopenia groups according t

SUBMITTER: Zhou D 

PROVIDER: S-EPMC10751414 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature