Impact of anthropometric parameters on outcomes in Asians with metabolic dysfunction-associated fatty liver disease.

ABSTRACT:

Background

We examined the incidence and predictors of clinical outcomes in metabolic dysfunction-associated fatty liver disease (MAFLD), focusing on anthropometric parameters.

Methods

Adult patients with MAFLD were identified in nationwide databases and a hospital cohort. Primary endpoints were atherosclerotic cardiovascular disease (ASCVD) and advanced fibrosis. Logistic and Cox regression analyses were used to analyse the association between anthropometric parameters and endpoints.

Results

In total, 4407 of 15 256 (28.9%) and 6274 of 25 784 subjects (24.3%) had MAFLD in the nationwide database; of these, 403 (9.2%) and 437 (7.0%) subjects were of lean/normal weight, respectively. Compared to the overweight/obese group, the lean/normal weight group had a significant

SUBMITTER: Choi KY 

PROVIDER: S-EPMC10751424 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature