Implementation of Recommendations on the Use of Corticosteroids in Severe COVID-19.

ABSTRACT:

Importance

Research diversity and representativeness are paramount in building trust, generating valid biomedical knowledge, and possibly in implementing clinical guidelines.

Objectives

To compare variations over time and across World Health Organization (WHO) geographic regions of corticosteroid use for treatment of severe COVID-19; secondary objectives were to evaluate the association between the timing of publication of the RECOVERY (Randomised Evaluation of COVID-19 Therapy) trial (June 2020) and the WHO guidelines for corticosteroids (September 2020) and the temporal trends observed in corticosteroid use by region and to describe the geographic distribution of the recruitment in clinical trials that informed the WHO recommendation.

Design, setting, and participants</

SUBMITTER: Camirand-Lemyre F 

PROVIDER: S-EPMC10751594 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature