Sustainable Sulfonic Acid Functionalized Tubular Shape Mesoporous Silica as a Heterogeneous Catalyst for Selective Unsymmetrical Friedel-Crafts Alkylation in One Pot.

ABSTRACT: The development of general and more sustainable heterogeneous catalytic processes for Friedel-Crafts (FC) alkylation reactions is a key objective of interest for the synthesis of pharmaceuticals and commodity chemicals. Sustainable heterogeneous catalysis for the typical FC alkylation of an easily accessible carbonyl electrophile and arenes or with two different arene nucleophiles in one-pot is a prime challenge. Herein, we present a resolution to these issues through the design and utilization of a mesoporous silica catalyst that has been functionalized with sulfonic acid. For the synthesis of sulfonic acid-functionalized mesoporous silica (MSN-SO₃H), thiol-functionalized mesoporous silica was first synthesized by the co-condensation method, followed by oxidation of the thiol f

SUBMITTER: Singh S 

PROVIDER: S-EPMC10751772 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature