Rabies post-exposure prophylaxis delivery to ensure treatment efficacy and increase compliance.

ABSTRACT:

Objectives

Since rabies is lethal once symptoms appear, its prevention including community awareness, mass dog vaccination and post-exposure prophylaxis (PEP) is crucial. Although safe and potent rabies vaccines have long been available, the global rabies burden is still high and access to adequately-delivered PEP remains challenging. Here we offer healthcare providers up-to-date, simple, exhaustive, visual guidance on how to perform PEP steps correctly.

Protocol

PEP consists of 1) washing the wound with water and soap for 15 min, 2) assessing the need for rabies biologicals based on specific criteria; 3) administering, if required, rabies immunoglobulin or monoclonal antibodies deep in and around all wounds; 4) starting, if necessary, the WHO-recommended intradermal 1-week

SUBMITTER: Nadal D 

PROVIDER: S-EPMC10752235 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature