Association between serum total bilirubin and diabetic kidney disease in US diabetic patients.

ABSTRACT:

Background

Bilirubin has been widely reported to be a protective factor against diabetic kidney disease (DKD) in Asian populations. However, few large-sample analyses have been conducted in American populations. This study aimed to investigate the association between serum total bilirubin (STB) level and DKD in a US diabetic cohort.

Methods

This cross-sectional study enrolled participants from the National Health and Nutrition Examination Survey (NHANES) 2003-2018. Univariate and multivariate logistic regression analyses were performed to assess the association between STB level and DKD. Three models were conducted to control the potential confounding factors. Subgroup analysis was carried out for further validation.

Results

Among the 5,355 participants, the median ag

SUBMITTER: Lv JM 

PROVIDER: S-EPMC10752268 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature