A design-based model of the aortic valve for fluid-structure interaction.

ABSTRACT: This paper presents a new method for modeling the mechanics of the aortic valve and simulates its interaction with blood. As much as possible, the model construction is based on first principles, but such that the model is consistent with experimental observations. We require that tension in the leaflets must support a pressure, then derive a system of partial differential equations governing its mechanical equilibrium. The solution to these differential equations is referred to as the predicted loaded configuration; it includes the loaded leaflet geometry, fiber orientations and tensions needed to support the prescribed load. From this configuration, we derive a reference configuration and constitutive law. In fluid-structure interaction simulations with the immersed boundary method, the

SUBMITTER: Kaiser AD 

PROVIDER: S-EPMC10752438 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature