Sensory neurons couple arousal and foraging decisions in Caenorhabditis elegans.

ABSTRACT: Foraging animals optimize feeding decisions by adjusting both common and rare behavioral patterns. Here, we characterize the relationship between an animal's arousal state and a rare decision to leave a patch of bacterial food. Using long-term tracking and behavioral state classification, we find that food leaving decisions in Caenorhabditis elegans are coupled to arousal states across multiple timescales. Leaving emerges probabilistically over minutes from the high arousal roaming state, but is suppressed during the low arousal dwelling state. Immediately before leaving, animals have a brief acceleration in speed that appears as a characteristic signature of this behavioral motif. Neuromodulatory mutants and optogenetic manipulations that increase roaming have a coupled increase in

SUBMITTER: Scheer E 

PROVIDER: S-EPMC10752585 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature