Doxorubicin-Loaded Microrobots for Targeted Drug Delivery and Anticancer Therapy.

ABSTRACT: Micro-sized magnetic particles (also known as microrobots [MRs]) have recently been shown to have potential applications for numerous biomedical applications like drug delivery, microengineering, and single cell manipulation. Interdisciplinary studies have demonstrated the ability of these tiny particles to actuate under the action of a controlled magnetic field that not only drive MRs in a desired trajectory but also precisely deliver therapeutic payload to the target site. Additionally, optimal concentrations of therapeutic molecules can also be delivered to the desired site which is cost-effective and safe especially in scenarios where drug dose-related side effects are a concern. In this study, MRs are used to deliver anticancer drugs (doxorubicin) to cancer cells and subsequent cell d

SUBMITTER: Mallick S 

PROVIDER: S-EPMC10753031 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature