Nanocellulose/Fe₃O₄/Ag Nanozyme with Robust Peroxidase Activity for Enhanced Antibacterial and Wound Healing Applications.

ABSTRACT: Peroxidase memetic nanozymes with their free radical-mediated catalytic actions proved as efficacious antibacterial agents for combating bacterial resistance. Herein, nanocellulose (NC) extracted from Eragrostis teff straw was used to prepare NC/Fe₃O₄/Ag peroxidase nanozyme as an antibacterial and wound healing agent. Characterization of the nanozyme with XRD, FTIR, SEM-EDX, and XPS confirmed the presence of silver NPs and the magnetite phase of iron oxide dispersed on nanocellulose. The peroxidase activity of the prepared nanozyme was examined using TMB and H₂O₂ as substrates which turned blue in acidic pH (λ_max = 652 nm). With a lower K_m (0.387 mM), the nanozyme showed a comparable affinity for TMB with that

SUBMITTER: Geleto SA 

PROVIDER: S-EPMC10753546 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature