Qualitative interview study exploring the perspectives of pregnant women on participating in controlled human infection research in the UK.

ABSTRACT:

Introduction

Pregnant women have been historically excluded from interventional research. While recent efforts have been made to improve their involvement, there remains a disparity in the evidence base for treatments available to pregnant women compared with the non-pregnant population. A significant barrier to the enrolment of pregnant women within research is risk perception and a poor understanding of decision-making in this population.

Objective

Assess the risk perception and influences on decision-making in pregnant women, when considering whether to enrol in a hypothetical interventional research study.

Design

Semistructured interviews were undertaken, and thematic analysis was undertaken of participant responses.

Participants

Twelve pregnant women were

SUBMITTER: Dorey RB 

PROVIDER: S-EPMC10753751 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature