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ABSTRACT: Background
Identifying youths most at risk to COVID-19-related mental illness is essential for the development of effective targeted interventions.Aims
To compare trajectories of mental health throughout the pandemic in youth with and without prior mental illness and identify those most at risk of COVID-19-related mental illness.Method
Data were collected from individuals aged 18-26 years (N = 669) from two existing cohorts: IMAGEN, a population-based cohort; and ESTRA/STRATIFY, clinical cohorts of individuals with pre-existing diagnoses of mental disorders. Repeated COVID-19 surveys and standardised mental health assessments were used to compare trajectories of mental health symptoms from before the pandemic through to the second lockdown.Results
Mental health trajectories differed significantly between cohorts. In the population cohort, depression and eating disorder symptoms increased by 33.9% (95% CI 31.78-36.57) and 15.6% (95% CI 15.39-15.68) during the pandemic, respectively. By contrast, these remained high over time in the clinical cohort. Conversely, trajectories of alcohol misuse were similar in both cohorts, decreasing continuously (a 15.2% decrease) during the pandemic. Pre-pandemic symptom severity predicted the observed mental health trajectories in the population cohort. Surprisingly, being relatively healthy predicted increases in depression and eating disorder symptoms and in body mass index. By contrast, those initially at higher risk for depression or eating disorders reported a lasting decrease.Conclusions
Healthier young people may be at greater risk of developing depressive or eating disorder symptoms during the COVID-19 pandemic. Targeted mental health interventions considering prior diagnostic risk may be warranted to help young people cope with the challenges of psychosocial stress and reduce the associated healthcare burden.
SUBMITTER: Qi L
PROVIDER: S-EPMC10753963 | biostudies-literature | 2023 Nov
REPOSITORIES: biostudies-literature
Qi Lu L Zhang Zuo Z Robinson Lauren L Bobou Marina M Gourlan Chantal C Winterer Jeanne J Adams Rebecca R Agunbiade Kofoworola K Zhang Yuning Y King Sinead S Vaidya Nilakshi N Artiges Eric E Banaschewski Tobias T Bokde Arun L W ALW Broulidakis M John MJ Brühl Rüdiger R Flor Herta H Fröhner Juliane H JH Garavan Hugh H Grigis Antoine A Heinz Andreas A Hohmann Sarah S Martinot Marie-Laure Paillère MP Millenet Sabina S Nees Frauke F van Noort Betteke Maria BM Orfanos Dimitri Papadopoulos DP Poustka Luise L Sinclair Julia J Smolka Michael N MN Whelan Robert R Stringaris Argyris A Walter Henrik H Martinot Jean-Luc JL Schumann Gunter G Schmidt Ulrike U Desrivières Sylvane S
BJPsych open 20231120 6
<h4>Background</h4>Identifying youths most at risk to COVID-19-related mental illness is essential for the development of effective targeted interventions.<h4>Aims</h4>To compare trajectories of mental health throughout the pandemic in youth with and without prior mental illness and identify those most at risk of COVID-19-related mental illness.<h4>Method</h4>Data were collected from individuals aged 18-26 years (<i>N</i> = 669) from two existing cohorts: IMAGEN, a population-based cohort; and E ...[more]