Ablation for atrial fibrillation improves the outcomes in patients with heart failure with preserved ejection fraction.

ABSTRACT:

Aims

Patients with heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) have worse clinical outcomes than those with sinus rhythm (SR). We aim to investigate whether maintaining SR in patients with HFpEF through a strategy such as AF ablation would improve outcomes.

Methods and results

This is a cohort study that analysed 1034 patients (median age 69 [63-76] years, 46.2% [478/1034] female) with HFpEF and AF. Of these, 392 patients who underwent first-time AF ablation were assigned to the ablation group, and the remaining 642 patients, who received only medical therapy, were assigned to the no ablation group. The primary endpoint was a composite of all-cause death or rehospitalization for worsening heart failure. After a median follow-up of 39 m

SUBMITTER: Xie Z 

PROVIDER: S-EPMC10754157 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature