Epinephrine in Cardiac Arrest: Identifying a Potential Limit for Resuscitation.

ABSTRACT:

Introduction

Epinephrine continues to be a fundamental part of the Advanced Cardiac Life Support algorithm despite a lack of evidence that it improves neurologically intact survival. Our aim was both to identify a potential upper limit of epinephrine use in resuscitations and to demonstrate real-world epinephrine use in different patient subgroups.

Methods

This was a single-center, retrospective cohort study, conducted between August 1, 2016-July 1, 2021, of patients with medical cardiac arrest who were administered a known number of epinephrine doses. The primary outcome was neurologically intact discharge defined by a modified Rankin scale ≤3, with secondary outcomes of comparing epinephrine doses by age, rhythm, and emergency medical services vs emergency department admin

SUBMITTER: Boivin Z 

PROVIDER: S-EPMC10754196 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature