Natural history and clinical burden of moderate aortic stenosis: a systematic review and explorative meta-analysis.

ABSTRACT:

Aims

The mortality risk of patients with moderate aortic stenosis is not well known, but recent studies suggested that it might negatively affect prognosis. We aimed to assess the natural history and clinical burden of moderate aortic stenosis and to investigate the interaction of patients' baseline characteristics with prognosis.

Methods

Systematic research was conducted on PubMed. The inclusion criteria were inclusion of patients with moderate aortic stenosis; and report of the survival at 1-year follow-up (minimum). Incidence ratios related to all-cause mortality in patients and controls of each study were estimated and then pooled using a fixed effects model. All patients with mild aortic stenosis or without aortic stenosis were considered controls. Meta-regression analy

SUBMITTER: Morelli M 

PROVIDER: S-EPMC10754483 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature