Sensory innervation of masseter, temporal and lateral pterygoid muscles in common marmosets.

ABSTRACT: Myogenous temporomandibular disorders is associated with an increased responsiveness of nerves innervating the masseter (MM), temporal (TM), and lateral pterygoid muscles (LPM). This study aimed to examine sensory nerve types innervating MM, TM and LPM of adult non-human primate-common marmosets. Sensory nerves were localized in specific regions of these muscles. Pgp9.5, marker for all nerves, and NFH, a marker for A-fibers, showed that masticatory muscles were primarily innervated with A-fibers. The proportion of C- to A-fibers was highest in LPM, and lowest in MM. All C-fibers (pgp9.5⁺/NFH^-) observed in masticatory muscles were peptidergic (CGRP⁺) and lacked mrgprD and CHRNA3, a silent nociceptive marker. TrpV1 was register in 17% of LPM nerves. All fiber

SUBMITTER: Hovhannisyan AH 

PROVIDER: S-EPMC10754842 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature