Thalamic functional connectivity and sensorimotor processing in neurodevelopmental disorders.

ABSTRACT: One of the earliest neurobiological findings in autism has been the differences in the thalamocortical pathway connectivity, suggesting the vital role thalamus plays in human experience. The present functional MRI study investigated resting-state functional connectivity of the thalamus in 49 (autistic, ADHD, and neurotypical) young adults. All participants underwent structural MRI and eyes-open resting state functional MRI scans. After preprocessing the imaging data using Conn's connectivity toolbox, a seed-based functional connectivity analysis was conducted using bilateral thalamus as primary seeds. Autistic participants showed stronger thalamic connectivity, relative to ADHD and neurotypical participants, between the right thalamus and right precentral gyrus, right pars opercularis-BA44

SUBMITTER: Karavallil Achuthan S 

PROVIDER: S-EPMC10755010 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature