Corticolimbic connectivity mediates the relationship between pubertal timing and mental health problems.

ABSTRACT:

Background

Undergoing puberty ahead of peers ('earlier pubertal timing') is an important risk factor for mental health problems during early adolescence. The current study examined pathways between pubertal timing and mental health via connectivity of neural systems implicated in emotional reactivity and regulation (specifically corticolimbic connections) in 9- to 14-year-olds.

Method

Research questions were examined in the Adolescent Brain Cognitive Development (ABCD) Study, a large population representative sample in the United States. Linear mixed models examined associations between pubertal timing and resting-state corticolimbic connectivity. Significant connections were examined as potential mediators of the relationship between pubertal timing and mental health (withd

SUBMITTER: Vijayakumar N 

PROVIDER: S-EPMC10755248 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature