Pairwise comparisons of three medication adherence outcomes in adolescents who use alcohol.

ABSTRACT:

Background

Accurate assessment of medication adherence is important for understanding pharmacotherapy outcomes across all phases of adolescent substance use disorder (SUD) clinical trials. The objective of this study was to describe and assess the pairwise concordance between three commonly used non-biological medication adherence assessment methods in adolescents who use alcohol to inform the selection of medication adherence measures for use in future youth SUD trials.

Methods

Participants (N = 32, 17-19-years-old) took N-acetylcysteine and placebo, in a randomized cross-over design, for 10 days each. Medication adherence was assessed (20 days total) via pill count, medication videos submitted twice daily, and the Medication Event Monitoring System (MEMS®). Lin's Concordan

SUBMITTER: Kirkland AE 

PROVIDER: S-EPMC10755249 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature