Postoperative outcomes of aspirin in microvascular free tissue transfer surgery-A systematic review and meta-analysis.

ABSTRACT: Microvascular free tissue transfer surgery is a frequently used technique for head and neck reconstruction involving anticoagulants, and the present study aimed to analyse the postoperative outcomes of aspirin use in conjunction with this procedure. We searched databases for articles published between 2007 and 2022 on microvascular free tissue transfer surgery using aspirin and assessed them for primary and secondary outcomes. Odds ratios (ORs) and 95 % confidence intervals (CIs) were determined through analyses, followed by constructing a forest plot for complication rates. A total of 617 articles were retrieved from the databases, including 14 original full-text articles. Overall complication rates ranged from 0.7-38 % (95 % CI, 17.85 ± 0.503 (±2.8 %) [17.347-18.353]), while flap surviva

SUBMITTER: Khan SA 

PROVIDER: S-EPMC10755481 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature