Exploring the theranostic potentials of miRNA and epigenetic networks in autoimmune diseases: A comprehensive review.

ABSTRACT:

Background

Autoimmune diseases (AD) are severe pathophysiological ailments that are stimulated by an exaggerated immunogenic response towards self-antigens, which can cause systemic or site-specific organ damage. An array of complex genetic and epigenetic facets majorly contributes to the progression of AD, thus providing significant insight into the regulatory mechanism of microRNA (miRNA). miRNAs are short, non-coding RNAs that have been identified as essential contributors to the post-transcriptional regulation of host genome expression and as crucial regulators of a myriad of biological processes such as immune homeostasis, T helper cell differentiation, central and peripheral tolerance, and immune cell development.

Aims

This article tends to deliberate and conceptualize

SUBMITTER: Nag S 

PROVIDER: S-EPMC10755504 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature