Rationale and design for the Blood Pressure Control Target in Diabetes (BPROAD) study.

ABSTRACT:

Background

Diabetes and hypertension are major modifiable risk factors for cardiovascular disease. Previous clinical trials have demonstrated that intensive blood pressure reduction lowers the risk of cardiovascular disease and all-cause mortality compared to standard blood pressure reduction among patients without diabetes. However, optimal levels of blood pressure control in patients with diabetes remain uncertain.

Methods

The Blood Pressure Control Target in Diabetes (BPROAD) study is a multicenter, randomized controlled trial conducted in mainland China. We plan to enroll 12 702 participants aged ≥50 years with type 2 diabetes, an increased cardiovascular risk, and systolic blood pressure ≥130 mm Hg from 150 study centers. Participants are randomly assigned to intensive

SUBMITTER: BPROAD Study Group 

PROVIDER: S-EPMC10755603 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature