Prevalence and prognostic value of baseline sarcopenia in hematologic malignancies: a systematic review.

ABSTRACT:

Background

The correlation between sarcopenia and hematological malignancy prognosis is still controversial. Design: A systematic review and meta-analysis. Objectives: To explore sarcopenia's prevalence and prognostic value in hematologic malignancies.

Data sources and methods

We searched Embase, MEDLINE, and Cochrane Library through Ovid SP using an appropriate search strategy on August 28, 2022, and updated the search results on January 9, 2023. Study quality was assessed using the Newcastle-Ottawa scale. The pooled prevalence of sarcopenia was calculated with a 95% confidence interval (CI). Relationships between sarcopenia and prognostic value were expressed as hazard ratio (HR) and 95% CI. HR means the probability of something undesirable, i.e., death or disease progress

SUBMITTER: Zeng X 

PROVIDER: S-EPMC10755879 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature