Structure-Function Relationship in Keratoconus: Spatial and Depth Vision.

ABSTRACT:

Purpose

The purpose of this study was to determine changes in spatial and depth vision with increasing severity of keratoconus and to model the structure-function relationship to identify distinct phases of loss in visual function with disease severity.

Methods

Best-spectacle corrected, monocular high-contrast visual acuity, contrast sensitivity function (CSF) and stereoacuity of 155 cases (16-31 years) with mild to advanced bilateral keratoconus was determined using standard psychophysical tests. Disease severity was quantified using the multimetric D-index. The structure-function relationship was modeled using linear, positive exponential, negative exponential, and logistic nonlinear regression equations.

Results

The logistic regression model explained the highest p

SUBMITTER: Kumar P 

PROVIDER: S-EPMC10756247 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature