Identification of dynamical changes of rabies transmission under quarantine: Community-based measures towards rabies elimination.

ABSTRACT: Quarantine has been long used as a public health response to emerging infectious diseases, particularly at the onset of an epidemic when the infected proportion of a population remains identifiable and logistically tractable. In theory, the same logic should apply to low-incidence infections; however, the application and impact of quarantine in low prevalence settings appears less common and lacks a formal analysis. Here, we present a quantitative framework using a series of progressively more biologically realistic models of canine rabies in domestic dogs and from dogs to humans, a suitable example system to characterize dynamical changes under varying levels of dog quarantine. We explicitly incorporate health-seeking behaviour data to inform the modelling of contact-tracing and exclusion

SUBMITTER: Rysava K 

PROVIDER: S-EPMC10756519 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature