Long-term occupational exposures on disability-free survival and mortality in older adults.

ABSTRACT:

Background

The impact of long-term occupational exposures on health in older adults is increasingly relevant as populations age. To date, no studies have reported their impact on survival free of disability in older adults.

Aims

We aimed to investigate the association between long-term occupational exposure and disability-free survival (DFS), all-cause mortality and cause-specific mortality in initially healthy older adults.

Methods

We analysed data from 12 215 healthy participants in the ASPirin in Reducing Events in the Elderly (ASPREE) study whose mean age was 75 years. Their work history was collated with the 'ALOHA-plus JEM' (Job Exposure Matrix) to assign occupational exposures. The primary endpoint, DFS, was a composite measure of death, dementia or persistent

SUBMITTER: Alif SM 

PROVIDER: S-EPMC10756660 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature