Novel Gluconobacter oxydans strains selected from Kombucha with potential postbiotic activity.

ABSTRACT: Gastric and colorectal cancer are among the most frequently diagnosed malignancies of the gastrointestinal tract. Searching for methods of therapy that complements treatment or has a preventive effect is desirable. Bacterial metabolites safe for human health, which have postbiotic effect, are of interest recently. The study aimed to preliminary assessment of the safety, antimicrobial, and anti-cancer activity of cell-free metabolites of Gluconobacter oxydans strains isolated from Kombucha beverages as an example of the potential postbiotic activity of acetic acid bacteria (AAB). The study material consisted of five AAB strains of Kombucha origin and three human cell lines (gastric adenoma-AGS, colorectal adenoma-HT-29, and healthy cells derived from the endothelium of the human umbilical v

SUBMITTER: Neffe-Skocinska K 

PROVIDER: S-EPMC10756867 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature