Prognostic Impact of Renal Function on 5-Year Outcomes After Fractional Flow Reserve-Guided Deferral of Revascularization.

ABSTRACT: Background Chronic kidney disease (CKD) might influence fractional flow reserve (FFR) value, potentially attenuating its prognostic utility. However, few large-scale data are available regarding clinical outcomes after FFR-guided deferral of revascularization in patients with CKD. Methods and Results From the J-CONFIRM registry (Long-Term Outcomes of Japanese Patients With Deferral of Coronary Intervention Based on Fractional Flow Reserve in Multicenter Registry), 1218 patients were divided into 3 groups according to renal function: (1) non-CKD (estimated glomerular filtration rate ≥60 mL/min per 1.73 m²), n=385; (2) CKD (estimated glomerular filtration rate 15-59 mL/min per 1.73 m², n=763); and (3) end-stage renal disease (ESRD) (eGFR <15 mL/min per 1.73 m²

SUBMITTER: Itakura R 

PROVIDER: S-EPMC10757552 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature