Association between the triglyceride glucose index and cognitive impairment and dementia: a meta-analysis.

ABSTRACT:

Background

The triglyceride and glucose (TyG) index is an alternative index of insulin resistance (IR). We aimed to clarify the relationship between the TyG index and cognitive impairment and dementia.

Methods

We conducted a comprehensive search of the PubMed, Cochrane Library, and Embase databases until February 2023 to identify relevant studies. Random-effects models were used to pool effect sizes, and the Grading of Recommendations Assessment, Development, and Evaluation system (GRADE) was used to assess the quality of the evidence.

Results

Ten studies were included, with seven of which investigated the relationship between the TyG index and cognitive impairment and three exploring the association between the TyG index and dementia. When the TyG index was described

SUBMITTER: Wang H 

PROVIDER: S-EPMC10757637 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature