Label-free biosensing with singular-phase-enhanced lateral position shift based on atomically thin plasmonic nanomaterials.

ABSTRACT: Rapid plasmonic biosensing has attracted wide attention in early disease diagnosis and molecular biology research. However, it was still challenging for conventional angle-interrogating plasmonic sensors to obtain higher sensitivity without secondary amplifying labels such as plasmonic nanoparticles. To address this issue, we developed a plasmonic biosensor based on the enhanced lateral position shift by phase singularity. Such singularity presents as a sudden phase retardation at the dark point of reflection from resonating plasmonic substrate, leading to a giant position shift on reflected beam. Herein, for the first time, the atomically thin layer of Ge₂Sb₂Te₅ (GST) on silver nanofilm was demonstrated as a novel phase-response-enhancing plasmonic materia

SUBMITTER: Zhu S 

PROVIDER: S-EPMC10757996 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature