Functional identification of PGM1 in the regulating development and depositing of inosine monophosphate specific for myoblasts.

ABSTRACT:

Background

Inosine monophosphate (IMP) is naturally present in poultry muscle and plays a key role in improving meat flavour. However, IMP deposition is regulated by numerous genes and complex molecular networks. In order to excavate key candidate genes that may regulate IMP synthesis, we performed proteome and metabolome analyses on the leg muscle, compared to the breast muscle control of 180-day-old Jingyuan chickens (hens), which had different IMP content. The key candidate genes identified by a differential analysis were verified to be associated with regulation of IMP-specific deposition.

Results

The results showed that the differentially expressed (DE) proteins and metabolites jointly involve 14 metabolic pathways, among which the purine metabolic pathway closely relat

SUBMITTER: Zhao W 

PROVIDER: S-EPMC10758172 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature