Case report: Thrombolysis in patients with acute ischemic stroke and cerebral cavernous malformation.

ABSTRACT:

Background

Cerebral cavernous malformation (CCM) is a rare disease associated with a latent risk of intracranial hemorrhage. However, due to limited evidence, the safety of recommending intravenous tissue plasminogen activators for patients with acute stroke and CCM remains uncertain.

Methods

Our study identified five patients with acute stroke and CCM treated between 2017 and 2023 across two hospitals. A comprehensive literature review was conducted, incorporating three similar case reports and two retrospective studies.

Results

Among 30 patients reviewed, three exhibited symptomatic intracranial hemorrhage, two of whom were women. Additionally, three patients presented with calcification in their CCM, with two experiencing symptomatic intracranial hemorrhage.

Con

SUBMITTER: Lin J 

PROVIDER: S-EPMC10758226 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature