The fermentation optimization for alkaline protease production by Bacillus subtilis BS-QR-052.

ABSTRACT:

Introduction

Proteases exhibit a wide range of applications, and among them, alkaline proteases have become a prominent area of research due to their stability in highly alkaline environments. To optimize the production yield and activity of alkaline proteases, researchers are continuously exploring different fermentation conditions and culture medium components.

Methods

In this paper, the fermentation conditions of the alkaline protease (EC 3.4.21.14) production by Bacillus subtilis BS-QR-052 were optimized, and the effect of different nutrition and fermentation conditions was investigated. Based on the single-variable experiments, the Plackett-Burman design was used to explore the significant factors, and then the optimized fermentation conditions, as well as the in

SUBMITTER: Sun B 

PROVIDER: S-EPMC10758460 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature