Multimorbidity Patterns and Rheumatoid Arthritis Disease Outcomes: Findings From a Multicenter, Prospective Cohort.

ABSTRACT:

Objective

To determine whether unique multimorbidity patterns are associated with long-term rheumatoid arthritis (RA) disease severity.

Methods

We conducted a cohort study within the Veterans Affairs Rheumatoid Arthritis registry. We applied previously derived multimorbidity patterns based on the presence of diagnostic codes for relevant conditions prior to enrollment using linked administrative data. Disease activity and functional status were assessed longitudinally up to 5 years after enrollment. The association of multimorbidity patterns with disease activity and functional status were assessed using generalized estimating equations models adjusting for relevant confounders.

Results

We studied 2,956 participants, of which 88.2% were male, 76.9% reported white race

SUBMITTER: Dutt S 

PROVIDER: S-EPMC10758525 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature