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Cyclization mechanism of monoterpenes catalyzed by monoterpene synthases in dipterocarpaceae.


ABSTRACT: Monoterpenoids are typically present in the secretory tissues of higher plants, and their biosynthesis is catalyzed by the action of monoterpene synthases (MTSs). However, the knowledge about these enzymes is restricted in a few plant species. MTSs are responsible for the complex cyclization of monoterpene precursors, resulting in the production of diverse monoterpene products. These enzymatic reactions are considered exceptionally complex in nature. Therefore, it is crucial to understand the catalytic mechanism of MTSs to elucidate their ability to produce diverse or specific monoterpenoid products. In our study, we analyzed thirteen genomes of Dipterocarpaceae and identified 38 MTSs that generate a variety of monoterpene products. By focusing on four MTSs with different product spectra a

SUBMITTER: Lu X 

PROVIDER: S-EPMC10758623 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature