Ambient air pollution and the dynamic transitions of stroke and dementia: a population-based cohort study.

ABSTRACT:

Background

Stroke and dementia are the leading causes of neurological disease burden. Detrimental effects of air pollution on both conditions are increasingly recognised, while the impacts on the dynamic transitions have not yet been explored, and whether critical time intervals exist is unknown.

Methods

This prospective study was conducted based on the UK Biobank. Annual average air pollution concentrations at baseline year 2010 estimated by land-use regression models were used as a proxy for long-term air pollution exposure. Associations between multiple air pollutants (PM_2.5, PM_2.5-10, and NO₂) indicated by air pollution score and the dynamic transitions of stroke and dementia were estimated, and the impacts during critical time intervals

SUBMITTER: Wang J 

PROVIDER: S-EPMC10758736 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature