Obstructive and restrictive spirometry from school age to adulthood: three birth cohort studies.

ABSTRACT:

Background

Spirometric obstruction and restriction are two patterns of impaired lung function which are predictive of poor health. We investigated the development of these phenotypes and their transitions through childhood to early adulthood.

Methods

In this study, we analysed pooled data from three UK population-based birth cohorts established between 1989 and 1995. We applied descriptive statistics, regression modelling and data-driven modelling to data from three population-based birth cohorts with at least three spirometry measures from childhood to adulthood (mid-school: 8-10 years, n = 8404; adolescence: 15-18, n = 5764; and early adulthood: 20-26, n = 4680). Participants were assigned to normal, restrictive, and obstructive spirometry based on adjusted regression resi

SUBMITTER: Ullah A 

PROVIDER: S-EPMC10758747 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature