Survival analysis and clinicopathological features of patients with stage IA lung adenocarcinoma.

ABSTRACT:

Background

With the development of medical technology and change of life habits, early-stage lung adenocarcinoma (LUAD) has become more common. This study aimed to systematically analyzed clinicopathological factors associated to the overall survival (OS) of patients with Stage IA LUAD.

Methods

A total of 5942 Stage IA LUAD patients were obtained from the Surveillance, Epidemiology, and End Results (SEER) database. Kaplan-Meier methods and log-rank tests were used to compare the differences in OS. A nomogram constructed based on the Cox regression was evaluated by Concordance index (C index), calibration curve, decision curve analysis (DCA) and area under curve (AUC). And 136 patients were recruited from Shandong Province Hospital for external validation.

Results

Cox

SUBMITTER: Li J 

PROVIDER: S-EPMC10758825 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature