Magnetically-actuated microcages for cells entrapment, fabricated by laser direct writing via two photon polymerization.

ABSTRACT: The manipulation of biological materials at cellular level constitutes a sine qua non and provocative research area regarding the development of micro/nano-medicine. In this study, we report on 3D superparamagnetic microcage-like structures that, in conjunction with an externally applied static magnetic field, were highly efficient in entrapping cells. The microcage-like structures were fabricated using Laser Direct Writing via Two-Photon Polymerization (LDW via TPP) of IP-L780 biocompatible photopolymer/iron oxide superparamagnetic nanoparticles (MNPs) composite. The unique properties of LDW via TPP technique enabled the reproduction of the complex architecture of the 3D structures, with a very high accuracy i.e., about 90 nm lateral resolution. 3D hyperspectral microscopy was empl

SUBMITTER: Popescu RC 

PROVIDER: S-EPMC10758856 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature